tratamiento del HPV

Prevention of HPV infection by human papillomavirus DNA by PCR techniques polymerase chain reaction and others

HPV MEDICAL CENTER and HPV MEDICAL GROUP has been created to prevent, to diagnose and treat HPV before it develops into cancer. For this purpose, we use DNA detection techniques (PCR and hybrid-capture) which allow us to make a diagnosis of the virus in its early stages of infection, also called “latent stage”. At the same time, these techniques let us know if the virus is benign or related to cancer being able to establish the risk of the infection.

Most of our members have been trained in our country and abroad and were awarded for their research projects and medical journals in International Medical Congresses.

One of our departments in our center is oriented to research in Clinical Pharmacology, working for the pharmaceutical industry with national and international laboratories, contributing to the development of new drugs. Part of our team has worked in the production of pharmaceutical drugs since the 60’s as well as in the development of new diagnostic techniques currently applied becoming pioneers in some areas of medicine. As a result of our work, we have successfully treated thousands of patients to date. We are continuously pushing ourselves to find new cures for diseases taking them as a challenge.


We have been working for more than three years in new therapeutic approaches to treat Human Papillomavirus in its different stages of infection.

These techniques were designed after several years of using classic therapeutic procedures such as the use of trichloroacetic acid, podophyllin, interferons, podophyllotoxin, electrocautery, leep, others, that produce regular results and suffering for the patients.

The main goal of our medical team is the treatment of human papillomavirus in clinical phase, and early stages.

Early detection and treatment of human papillomavirus allowed us to perform new therapeutic approaches that will be communicated in medical congresses and published shortly.

The certain diagnose most be done by molecular biology.

Using molecular pathology techniques, the HPV test, unlike the Pap smear, allows us to have a precise diagnosis of the Human Papillomavirus. The Polymerase Chain Reaction (PCR) is a painless technique which involves the extraction of cellular material as it is done in a Pap smear but, unlike this, it has a sensitivity of 100% in the cervix. In other words, there is no possibility of false negatives if the extraction is correctly performed. This molecular biology technique, which we prefer and recommend, also gives us the possibility to find out which type of HPV the patient actually has. The importance of this lies in the fact that there are tumor viruses, in other words, viruses related to cancer such as: HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68, among others. There are other viruses related to benign warts which may result unsightly or contagious. This technique is also used in other genital areas such as the vagina, vulva, anus, penis or other parts of the body, which cannot be contagious, such as the mouth or areas of the skin near the genitals and different organs where the HPV infections are less frequent, on the other hand PCR lets us know if HPV vaccines will be preventive or not

Another currently used technique for detection of the HPV is the “hybrid-capture” test which gives us the possibility to obtain information about the human papillomaviruses connected to genital infection or cervix cancer as well as some benign viruses related to common warts. Unlike PCR, this technique does not report on the infectious type of viruses and it is only sensitive to the most frequently found viruses.
The “hybrid-capture” detects HPV viruses which are often found in the genitals. These one are classified in: Group I: 6, 11, 42, 43, 44, 53 and 54 called “low-risk” HPV types and which are not related to cancer; and Group II viruses, also called of “high-risk”: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68 related cancer.

HPV (Human Papillomavirus), can be considered a transforming agent thus called tumoral viruses.

Tumoral viruses such as some types of HPV cause the transformation of a normal into a cancerous cell. This is a result of HPV  ability to integrate its genetic information (HPV DNA) into the nuclear DNA of the host cell. Some HPV oncoproteins play an important role in this transformation.

Currently two vaccines are available.

The first GARDASIL, prevents against HPV viruses (subtypes16 and 18) responsible for 50% and 20% of Cervical Cancer  respectively, as clinical trials made refer, and genital warts produced by this types of HPV. It also protects against HPV viruses (subtypes 6 and 11) responsible for 90% of genital warts that are not related to cancer.

The second CERVARIX, vaccine prevents against HPV viruses 16 and 18 and is credited with cross protection against HPV 45, thus prevent against Cervical Cancer by 75% (70% of cervical cancers attributed to HPV 16 and 18 and the remaining 5% to HPV-45).

The best age to apply the vaccine is before sexual initiation, because protection is guaranteed for 6 to 8 years.  For example a teenager who applies the vaccine at age 14 is protected until the 20 to 22 years. The need for a booster after 6 years is on study.

A woman who already has relations should exclude the presence of HPV before the vaccination.  In this way we can evaluate the real effectiveness.   Here we must clarify that there are many cases where patients refers a history of normal gynecologic controls and have a viral infection not detected. The decision to apply the vaccine to women who have initiated sexual activity should be well founded.  To rule out the presence or absence of HPV is necessary a DNA study called Polymerase Chain Reaction (PCR).

This is very important and not said by the laboratories. Lots of collateral effects like paralysis have been attributed to the vaccine.

There are other HPV viral subtypes that are associated with cervical cancer and others and not prevented by the vaccines, therefore people who already have been vaccinated must continue with gynecological checks.

-If a person is infected with any of the HPV virus that protects against the vaccine, it will not be effective against it.

-If a person is infected with any type of HPV should avoid vaccination.

Consult us info@hpvmedicalcenter.com.ar